Programme
The CSSB Symposium 2023 will focus on the biology of infections and highlight different key cellular processes leading to pathogen proliferation. The symposium will take place 3-5 May 2023 in Hamburg, Germany. The programme for the symposium can be found below.
Day 1: May 3, 2023
| 12:00 - Registration | |
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| Welcome Address / Key Note Lecture | |
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| Time: | Speakers: |
| 13:00 | Welcome Address Kay Grünewald, CSSB Scientific Director and Tim Gilberger, CSSB Group Leader |
| 13:10 | Key Note Lecture: From molecules to disease eradication: Getting the upper hand on malaria Dyann Wirth, Harvard University, USA |
| Session 1: “Invasion strategies” |
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|---|---|
| Time: | Speakers: |
| 14:10 | Session Introduction Christian Löw and Maria Garcia Alai |
| 14:20 | Blood and Guts: Malaria Parasite Entry and Transmission Wai Hong Tham, WEHI, Australia |
| 14:50 | Origin and arrangement of actin filaments in apicomplexan parasites for gliding motility revealed by cryo-electron tomography Matthew Martinez, University of Pennsylvania, USA |
| 15:05 | Structural and functional analysis of natural capsid variants suggests sialic acid-independent entry of BK polyomavirus Marie Sorin, Nantes University, France |
| 15:20 | Coffee Break |
| 16:10 | Development of a novel antiinfective that blocks invasion of Salmonella Samuel Wagner, The University of Tübingen, Germany |
| 16:40 | A Microtubule-Associated Protein Is Essential for Malaria Parasite Transmission Paolo Mesen-Ramirez, CSSB – Bernhard Nocht Institute for Tropical Medicine, Germany |
| 16:55 | Mapping herpes simplex virus 1 membrane proteins in native environments using signpost origami tags (SPOTs) Emily Machala, CSSB – Universität Hamburg |
| 17:10 | Science Slam for posters, Thomas Marlovits |
| 17:45 | Poster Session - Networking Buffet |
Day 2: May 4, 2023
| Session 2: “Persistance and proliferation strategies” | |
|---|---|
| Time: | Speakers: |
| 09:00 | Session Introduction Meytal Landau and Michael Kolbe |
| 09:10 | Protein ubiquitination and host defence. Katrin Rittinger, The Francis Crick Institute, United Kingdom |
| 09:40 | Uncovering molecular mechanism of intra-molecular phosphotransfer in bacterial signal transduction Badri Nath Dubey, CSSB – Deutsches Elektronen-Synchrotron DESY, Germany |
| 09:55 | Proteome-spanning structure predictions of herpesvirus protein interaction networks Timothy Soh, CSSB – Hannover Medical School / Leibniz Institute of Virology, Germany |
| 10:10 | Coffee Break |
| 10:40 | Structure and function of the chemosensory system of Spirochetes and its involvement in infection and persistence Ariane Briegel, Leiden University, The Netherlands |
| 11:10 | Correlative microscopy studies on Shigella T3SS using in situ and in vitro conditions Fereshta Hafizi, CSSB – Helmholtz Centre of Infection, Germany |
| 11:25 | Macrolide esterases hiding in plain sight Antonio Ruzzini, University of Saskatchewan, Canada |
| 11:40 | Meet the Speakers and Lunch Break |
| Session 3: “Resistance strategies” | |
|---|---|
| Time: | Speakers: |
| 12:40 | Session Introduction Jens Bosse and Rainer Kaufmann |
| 12:50 | IRoles and mechanisms of cellulose secretion across Gram-negative bacteria Petya Violinova Krasteva, European Institute of Chemistry and Biology, France |
| 13:20 | In situ ribosome clustering and ultrastructure reorganisation of polar tube proteins in germinated microsporidia polar tube Himanshu Sharma, Umeå University, Sweden |
| 13:35 | An RNA to rule them all: Critical steps in Lassa virus RNP assembly and recruitment Lennart Sänger, CSSB – Leibniz Institute of Virology / Deutsches Elektronen-Synchrotron DESY, Germany |
| 13:50 | Resistance-guided antibiotic discovery Gerry Wright, McMaster University, Canada |
| 14:20 | Membrane activity and species specificity of the fungal peptide toxin candidalysin Thomas Gutsmann, Research Centre Borstel, Germany |
| 14:35 | Structural journey of an insecticidal protein against western corn rootworm Guendalina Marini, CSSB – University Medical Center Hamburg-Eppendorf, Germany |
| 14:50 | Coffee Break |
| Session 4: “Egress strategies” | |
|---|---|
| Time: | Speakers: |
| 15:20 | Session Introduction Ulrike Laugks and Jan Kosinski |
| 15:30 | A new class of potent neutralizing human monoclonal antibodies targeting the Hepatitis E virus ORF2 protein Thomas Krey, Universität zu Lübeck, Germany |
| 16:00 | ER-dependent membrane repair of mycobacteria-induced vacuole damage Aby Amand, University of Osnabrück, Germany |
| 16:15 | Insights into alphaviral genome capping – A mechanistic study Karim Rafie, Umeå University, Sweden |
| 16:30 | Egress of P. falciparum from erythrocytes and the role of the merozoite surface protein MSP1 Helen Saibil, Birkbeck, UK |
| 17:00 | GExtensive profiling of virus-host protein interaction contact sites from intact HSV-1 infected cells Boris Bodganov, Leibniz Instute for Molecular Pharmacology, Germany |
| 17:15 | In situ structural studies of poliovirus assembly reveals membrane-assisted assembly and selective autophagosome packaging Lars-Anders Carlson, Umeå University, Sweden |
| 17:45 | Coach transfer to Hamburg Harbour (Landungsbrücken) |
| 18:30 | Harbour/Elbe Cruise with Dinner |
Day 3: May 5, 2023
| Session 5: “Transmission strategies” | |
|---|---|
| Time: | Speakers: |
| 09:00 | Session Introduction Maya Topf and Charlotte Uetrecht |
| 09:10 | Organelle Remodeling: Intra- and Inter-Cellular Communication during Infection Ilena Cristea, Princeton University, USA |
| 09:40 | Contribution of Actin-like proteins Alp1 and Alp2b to Plasmodium transmission Ross Douglas, University of Giessen, Germany |
| 09:55 | How influenza A virus escapes the nucleus Jan Kosinski, CSSB – EMBL Hamburg, Germany |
| 10:10 | Coffee Break |
| 10:45 | Host cell modification by HSV-1 Colin Crump, Cambridge University, UK |
| 11:15 | Revealing the structural basis of phenuivirus genome transcription via cap-snatching Harry Williams, Bernhard Nocht Institute for Tropical Medicine, Germany |
| 11:30 | Blocking interactions of Plasmodium falciparum 6-cysteine proteins using inhibitory nanobodies Mealanie Dietrich, Walter and Eliza Hall Institute of Medical Research, The University of Melbourne, Australia |
| 11:45 | Poster Prize Award Ceremony |
| 12:00 | Closing Remarks, Holger Sondermann |
| 12:05 | Lunch and Finish |
| 13:00 | Core Facility Tour (Optional) |
